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IBEX Sciences Calcium Chloride 0.025 mol/L (Molarity: 0.025 M) Solution is a ready-to-use (RTU), standardized liquid chemical reagent heavily utilized in medical diagnostics and general analytical chemistry. [1, 2, 3, 4]
Primary Medical and Diagnostic Applications
In clinical hematology and coagulation laboratories, this exact concentration is crucial for Hemostasis testing:
- Activated Partial Thromboplastin Time (APTT) Assays: Blood is typically collected in sodium citrate tubes, which temporarily prevent clotting by binding (chelating) calcium ions. To measure how long it takes for a clot to form during an APTT test, the intrinsic pathway must be re-activated. Adding a precise dose of 0.025 mol/L Calcium Chloride (recalcification) overrides the citrate, restarting the coagulation cascade to measure clot formation times accurately. [1]
- Instrument Versatility: This reagent is optimized to work smoothly with optical, mechanical, or opto-mechanical automated coagulation analyzer detection systems. [1]
Key Product Features
- Ready-to-Use (RTU): Formulated under rigorous standards, eliminating tedious calculations, measurement errors, or water purity issues during lab preparation. [1]
- Analytical standard: Used as a reference standard in EDTA-based complexometric titrations where a precise Ca²⁺ value determines sharp end-points. [1]
Storage, Handling, and Stability
- Temperature: Usually stored sealed between 2°C and 25°C (or ambient room temperature up to 30°C depending on specific packaging instructions).
- Evaporation Warning: The bottle must remain tightly capped when not actively dispensing. Evaporation reduces the water content, inadvertently increasing the 0.025 mol/L concentration and compromising diagnostic accuracy.
- Stability: Stable until the labeled expiration date when unopened. Most open vials in high-throughput environments carry an on-board stability limit of roughly 8 weeks if uncontaminated. [1, 2]
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