The “Frog V.S. (Vertical Section) Skin Model” (Blister Series) by IBEX SCIENCES is a three-dimensional, vacuum-formed plastic relief model designed for histology, zoology, and general biology studies. [1, 2, 3]
The abbreviation “V.S.” stands for Vertical Section (or cross-section), indicating that the model shows a microscopic slice through the layers of an amphibian’s skin. This lightweight “blister” format features a highly magnified, color-coded raised profile, enabling students to explore structural-functional adaptations of amphibian skin—such as cutaneous respiration and moisture retention—without needing a microscope. [1, 2]
The model highlights the structural anatomy of a frog’s skin, typically divided into the following key layers and components: [1, 2]
1. Epidermis (Outer Layer)
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- Stratum Corneum: The outermost, very thin layer of keratinized cells that acts as a protective shield while remaining permeable enough to allow for gas exchange and water absorption. [1]
- Stratum Germinativum (Basal Layer): The deepest layer of the epidermis where continuous cell division occurs to replace shed outer skin cells. [1]
2. Dermis (Inner Layer)
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- Stratum Spongiosum: The upper, loose layer of the dermis that is highly vascularized and contains the skin’s functional glands.
- Stratum Compactum: The deeper, dense layer of connective tissue composed of horizontal collagen fibers that give the skin its durability and elasticity. [1]
3. Specialized Cutaneous Structures
- Mucus Glands: Plentiful, spherical glands embedded in the dermis that secrete a slimy coating onto the surface. This keeps the skin moist, which is absolutely vital for cutaneous respiration (breathing through the skin). [1, 2, 3]
- Poison Glands (Granular Glands): Larger dermal glands that produce toxic or foul-tasting secretions to ward off predators. [1, 2]
- Chromatophores (Pigment Cells): Star-shaped branching cells located at the border of the epidermis and dermis. These cells contain pigments responsible for the frog’s color patterns and camouflage capabilities. [1, 2, 3]
- Capillary Network: A rich supply of superficial blood vessels wrapping around the glands, illustrating how oxygen is absorbed directly from the environment into the bloodstream. [1]





















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