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The Sodium Fluoride (NaF) Solution provided by IBEX SCIENCES is a high-purity chemical reagent widely utilized across biological research, analytical chemistry, and medical educational environments. Because sodium fluoride dissolves readily in water to release active fluoride ions, it serves multiple precise laboratory applications. [1, 2, 3, 4, 5]
Primary Laboratory Applications
- Hematology & Blood Sample Preservation:
In clinical or research settings studying blood chemistry, sodium fluoride is a powerhouse antiglycolytic agent. It functions by chemically inhibiting enolase, a crucial enzyme in the glycolysis pathway. By stopping red blood cells from consuming glucose, it preserves the exact glucose concentration of a sample over extended periods. It is frequently paired with an anticoagulant like potassium oxalate for comprehensive blood-tube stability. [1, 2] - Enzyme Inhibition in Biochemistry (Phosphatase Inhibitor):
Sodium fluoride functions as a potent, reversible inhibitor of several key metabolic enzymes. It is heavily incorporated into cell lysis and extraction buffers to selectively suppress: - Analytical Chemistry & Environmental Metrics:
Used as a volumetric standard solution or a fluoride molarity calibration benchmark. It allows researchers to safely configure ion-selective electrode (ISE) probes to accurately measure fluoride toxicity levels in municipal water treatment studies. [1, 2, 3, 4] - Educational Science Demonstrations:
Supplied to clinical and academic science laboratories to demonstrate enzyme-blocking reactions or to perform qualitative stoichiometric experiments. [1, 2, 3]
Standard Solution Specifications
- Form: Clear, colorless, and odorless aqueous liquid.
- Chemical Profile: Highly stable at typical ambient room temperatures (15°C to 25°C), provided the container remains airtight.
- Material Sensitivity: Highly concentrated fluoride solutions can chemically etch glass. Depending on the concentration grade supplied by the manufacturer, it may be shipped and stored in specialized, high-density polyethylene (HDPE) plastic containers. [1, 2, 3, 4, 5]
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